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How Are Antibiotic-resistant HAIs a Threat to All Patients?

Antibiotic-resistant HAIs are a threat to all patients across the entire continuum of care. 

  • HAIs are commonly caused by antibiotic-resistant bacteria, which may lead to sepsis or death. One in seven catheter- and surgery-related HAIs in acute care hospitals, and one in four catheter- and surgery-related HAIs in long-term acute care hospitals, is caused by any of six resistant bacteria (not including C. difficile).
  • These six bacteria are among the most deadly antibiotic-resistant bacteria, identified as urgent or serious threats by CDC: CRE (carbapenem-resistant Enterobacteriaceae), MRSA (methicillin-resistant Staphylococcus aureus ), ESBL-producing Enterobacteriaceae (extended-spectrum ß-lactamases), VRE (vancomycin-resistant enterococci), multi-drug resistant pseudomonas, and multi-drug resistant Acinetobacter.
  • Progress has been made in preventing HAIs, including a 50% decrease in central line-associated blood stream infections from 2008 to 2014, but more work is needed.
  • C. difficile is the most common type of bacteria responsible for infections in hospitals. Most C. difficile is not resistant to the antibiotics used to treat it, but antibiotic use puts patients at high risk for deadly diarrhea.

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